OSARA is a widely-used accessibility extension for REAPER, designed for Windows and macOS. However, Cody Tyler Hurst has recently ported the code to Linux, with most functionality supported. You can read more about the supported functionality and limitations at the link below.
Via GitHub:
A Linux port of OSARA — accessibility for the REAPER digital audio workstation. Upstream OSARA targets Windows and macOS; this project adds the platform pieces needed to make REAPER usable for blind musicians on Linux.
Please note that this is an unofficial solution.
